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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNJ5 All Species: 11.52
Human Site: S412 Identified Species: 25.33
UniProt: P48544 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48544 NP_000881.3 419 47669 S412 E P K G L G G S R E A R G S V
Chimpanzee Pan troglodytes XP_508857 330 37659
Rhesus Macaque Macaca mulatta XP_001113289 429 48853 S422 E P K R L G G S R E A R G S V
Dog Lupus familis XP_546402 419 47408 A412 E P E G L S G A R G N R G S V
Cat Felis silvestris
Mouse Mus musculus P48545 419 47571 S412 E P N G L S V S Q A T R G S M
Rat Rattus norvegicus P48548 419 47764 S412 E P N G L S V S R A T R G S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509759 885 96895 N865 E T E D E E K N H E E Q T E R
Chicken Gallus gallus Q90854 492 55398 G472 K L Q K L S G G G R M E G N L
Frog Xenopus laevis NP_001156864 429 49473 E420 N G A P L G S E D L N R R T Q
Zebra Danio Brachydanio rerio XP_700619 425 48766 S417 P P E T N N G S A N R L E E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52192 505 57401 N452 S N S P V F S N N H S K F N T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 96.2 94 N.A. 93.3 93.7 N.A. 36.6 48.9 73.4 72.7 N.A. N.A. N.A. 34.4 N.A.
Protein Similarity: 100 77.3 97.4 96.4 N.A. 95.9 96.4 N.A. 40.9 63.2 81.3 83 N.A. N.A. N.A. 52.2 N.A.
P-Site Identity: 100 0 93.3 66.6 N.A. 53.3 60 N.A. 13.3 20 20 20 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 0 93.3 80 N.A. 66.6 66.6 N.A. 33.3 46.6 26.6 26.6 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 10 10 19 19 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 55 0 28 0 10 10 0 10 0 28 10 10 10 19 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 10 0 37 0 28 46 10 10 10 0 0 55 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 19 10 0 0 10 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 64 0 0 0 0 10 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 19 % M
% Asn: 10 10 19 0 10 10 0 19 10 10 19 0 0 19 10 % N
% Pro: 10 55 0 19 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 10 0 0 10 0 0 10 % Q
% Arg: 0 0 0 10 0 0 0 0 37 10 10 55 10 0 10 % R
% Ser: 10 0 10 0 0 37 19 46 0 0 10 0 0 46 0 % S
% Thr: 0 10 0 10 0 0 0 0 0 0 19 0 10 10 10 % T
% Val: 0 0 0 0 10 0 19 0 0 0 0 0 0 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _